Retinal Disease Image Analysis Reading Center
 
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University Hospitals - Case Dept of Ophthalmology

 

 

 

What is REDIARC?

The Retinal Disease Image Analysis Reading Center is an independently funded research subunit of the Center for Visual Sciences, Department of Ophthalmology at Case Western Reserve University located at the University Hospitals Case Medical Center. Dr. Suber Huang serves as Principal Investigator for REDIARC, in addition to serving as Professor and Vice-Chairman of Ophthalmology at CASE, Director of Vitreoretinal Diseases and Surgery at University Hospitals Case Medical Center and Director of Ophthalmology Clinical Research. Conceived in 2000, REDIARC currently serves as a Reading Center for masked analysis of imaging data obtained in prospective, multi-center, clinical trials. Data is used to evaluate the safety, efficacy, or progression of retinal diseases as documented by retinal fundus and/or fluorescein angiographic imaging of the retinal vasculature. REDIARC has the capability to analyze both film and digital data.

Current research -

This section is currently being updated.

Previous projects include four asynchronous studies of the safety and efficacy of fluocinolone acetonide delivered by a unique intravitreal delivery device (Envison TD, patented, Bausch and Lomb) in the treatment of non-infectious ocular inflammatory disease (uveitis). A separate study also assesses the use of this device for the treatment of unresponsive diabetic macular edema as a cause of chronic visual loss. Other studies include the evaluation of retinal vascular changes in Alzheimer’s disease in affected patients, unaffected siblings, and in an age-matched cohort. REDIARC also serves as the designated data analysis center for the APEX 2003 expedition, a multidisciplinary study of the effects of severe altitude on the retina conducted in the Bolivian Andes. Together, REDIARC currently expects to analyze 500,000 images from 128 clinical sites located in 23 countries over a 6 year period.

Capabilities -


REDIARC seeks to continue to provide objective masked data analysis for clinical studies. REDIARC intends to use telemedicine and remote diagnostic capabilities to study diabetic retinopathy. REDIARC-funded database research using Markovian modeling has produced a more efficient algorithm for screening. It is hoped that a strategy for widespread screening of diabetic complications can be profitably utilized to prevent blinding complications in the uninsured and under-insured. Effective utilization of resources has significant consequences for developing a world-wide, international screening strategy.

In partnership with the Specular Microscopy Reading Center at University Hospitals Case Medical Center and the OCT Reading Center at Duke University, REDIARC actively seeks engagement in other clinical studies including: Macular Degeneration, Diabetes, Glaucoma, and Corneal Diseases.

 

 

 
 
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